Toluene

Toluene

SCHEMBL6257976

CCCCCC.CCCCCC.Cc1ccccc1.Cc1ccccc1

nearest known ligand 0.65

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
LMNA P02545 1/20 0.65
ALOX12 P18054 1/20 0.65
ACHE P22303 1/20 0.65
HTT P42858 1/20 0.50
PCSK9 Q8NBP7 1/20 0.48
LTA4H P09960 2/20 0.45
SIGMAR1 Q99720 1/20 0.45
CES2 O00748 2/20 0.43
CES1 P23141 2/20 0.43
DNM1 Q05193 1/20 0.43
MEN1 O00255 1/20 0.42
TP53 P04637 1/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
EPHX2 P34913 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL18640410 1.00 TSHR (0.65) TSHRLMNAALOX12ACHEHTT
Toluene SCHEMBL2990240 1.00 TSHR (0.65) TSHRLMNAALOX12ACHEHTT
Toluene SCHEMBL4250303 1.00 TSHR (0.65) TSHRLMNAALOX12ACHEHTT
Toluene SCHEMBL80497 1.00 TSHR (0.65) TSHRLMNAALOX12ACHEHTT
Toluene SCHEMBL1549759 1.00 TSHR (0.65) TSHRLMNAALOX12ACHEHTT
Toluene SCHEMBL10941851 1.00 TSHR (0.65) TSHRLMNAALOX12ACHEHTT
Toluene SCHEMBL27455870 1.00 TSHR (0.65) TSHRLMNAALOX12ACHEHTT
Toluene SCHEMBL27422075 1.00 TSHR (0.65) TSHRLMNAALOX12ACHEHTT
Octane SCHEMBL11193559 0.97 TSHR (0.61) TSHRLMNAALOX12ACHEHTT
Decane SCHEMBL7261270 0.97 TSHR (0.61) TSHRLMNAALOX12ACHEHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005072178-A2 METHOD FOR PREPARING AN EPOXIDIZED FUNCTIONAL VEGETABLE OIL BIOBASE CHEMICAL (US) 2005-08-11 WO disclosed
US-6127130-A MEASUREMENT OF TARGET PROTEIN AND BLOCKING AGENT IN A SAMPLE USING ANTIBODIES; PREPARING A CALIBRATED PROTEIN SOLUTION AND BLOCKING AGENTS, GRAPHING RESPONSES FOR COMPETETIVE AND NONCOMPETETIVE BINDING THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2000-10-03 US disclosed