Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 19/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2882247 | 0.88 | HPGD (0.56) | HPGD | |
| SCHEMBL2882246 | 0.88 | HPGD (0.56) | HPGD | |
| SCHEMBL2877670 | 0.84 | HPGD (0.52) | HPGDPTPN1AKR1B1GSK3BRAB9A | |
| SCHEMBL6422799 | 0.84 | HPGD (0.52) | HPGDPTPN1AKR1B1GSK3BRAB9A | |
| SCHEMBL2877667 | 0.84 | HPGD (0.52) | HPGDPTPN1AKR1B1GSK3BRAB9A | |
| SCHEMBL2880319 | 0.78 | PIK3CD (0.48) | HPGDAKR1B1RAB9A | |
| SCHEMBL2880317 | 0.78 | PIK3CD (0.48) | HPGDAKR1B1RAB9A | |
| SCHEMBL2883618 | 0.76 | PDE4B (0.58) | HPGDGSK3B | |
| SCHEMBL2883617 | 0.76 | PDE4B (0.58) | HPGDGSK3B | |
| SCHEMBL2882116 | 0.74 | HPGD (0.56) | HPGDPTPN1AKR1B1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531813-A1 | USE OF COMPOUNDS FOR INCREASING SPERMATOZOA MOTILITY | Applied Research Systems ARS Holding N.V. (AN) | 2005-05-25 | — | — | EP | claimed |
| WO-2004006916-A1 | USE OF COMPOUNDS FOR INCREASING SPERMATOZOA MOTILITY | APPLIED RESEARCH SYSTEMS ARS HOLDING NV (AN) | 2004-01-22 | — | — | WO | claimed |