Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 17/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4869424 | 0.84 | AOC3 (0.65) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL4990368 | 0.81 | AOC3 (0.67) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL6392582 | 0.80 | AOC3 (0.65) | AOC3MAOBSMN1; SMN2KMT2A | |
| SCHEMBL4876122 | 0.79 | AOC3 (0.71) | AOC3MAOBSMN1; SMN2KMT2A | |
| SCHEMBL4871898 | 0.79 | AOC3 (0.71) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL27634179 | 0.79 | AOC3 (0.74) | AOC3MAOBSMN1; SMN2KMT2A | |
| SCHEMBL4865974 | 0.79 | AOC3 (0.58) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL4870646 | 0.78 | AOC3 (0.68) | AOC3MAOBSMN1; SMN2KMT2A | |
| SCHEMBL3934843 | 0.78 | AOC3 (0.60) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL3931009 | 0.78 | AOC3 (0.61) | AOC3MAOBSMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608365-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | Sucampo AG (CH) | 2005-12-28 | — | — | EP | disclosed |
| EP-1587800-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS | Astellas Pharma Inc. (JP) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004087138-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | SUCAMPO AG (CH) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004067521-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-08-12 | — | — | WO | disclosed |