Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 18/20 | 0.73 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.51 |
| ▸ | FPR3 | P25089 | 1/20 | 0.49 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259514 | 1.00 | CCR1 (0.73) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL6703593 | 1.00 | CCR1 (0.73) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL5056373 | 0.93 | CCR1 (0.73) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL6254386 | 0.93 | CCR1 (0.72) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL6253470 | 0.93 | CCR1 (0.72) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL6254136 | 0.92 | CCR1 (0.71) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL6279863 | 0.92 | CCR1 (0.71) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL6256840 | 0.92 | CCR1 (0.71) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL6252447 | 0.90 | CCR1 (0.75) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL5059532 | 0.90 | CCR1 (0.78) | CCR1PTGDR2FPR3GPR65GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572704-A1 | PHOSPHORUS-CONTAINING PIPERAZINE DERIVATIVES AS CCR1 ANTAGONISTS | Pfizer Products Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004055031-A1 | PHOSPHORUS-CONTAINING PIPERAZINE DERIVATIVES AS CCR1 ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2004-07-01 | — | — | WO | disclosed |