Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 12/20 | 0.75 |
| ▸ | DRD2 | P14416 | 6/20 | 0.64 |
| ▸ | DRD3 | P35462 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009560 | 0.90 | DRD4 (0.73) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL4005935 | 0.87 | DRD4 (0.72) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL4009676 | 0.86 | DRD4 (1.00) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL4003541 | 0.85 | DRD4 (0.76) | DRD4DRD2DRD3CYP2C9CYP2C19 | |
| SCHEMBL6213269 | 0.83 | DRD4 (0.75) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL4002702 | 0.82 | DRD4 (0.77) | DRD4DRD2DRD3 | |
| SCHEMBL4005465 | 0.82 | DRD4 (0.78) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL6211655 | 0.82 | DRD4 (0.66) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL6264871 | 0.82 | DRD4 (0.80) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL6214661 | 0.82 | DRD4 (0.70) | DRD4DRD2DRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | claimed |