Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.67 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.67 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.67 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.67 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.67 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.67 |
| ▸ | GPR183 | P32249 | 1/20 | 0.67 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.67 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.58 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259828 | 1.00 | S1PR1 (0.67) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL6260199 | 1.00 | S1PR1 (0.67) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| Hydrochloric Acid SCHEMBL8499753 | 0.95 | S1PR1 (0.70) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL8499518 | 0.94 | S1PR1 (0.67) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL3393258 | 0.93 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL3394918 | 0.93 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL3391015 | 0.93 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL3393863 | 0.93 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL3393720 | 0.93 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 | |
| SCHEMBL3389424 | 0.93 | S1PR1 (0.73) | S1PR1S1PR4S1PR3S1PR5TNNC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014603-A1 | PHOSPHINANE COMPOUNDS WITH IMMUNOMODULATING ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |