Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 14/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 14/20 | 0.40 |
| ▸ | ITGAL | P20701 | 14/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218451 | 0.90 | ITGB2 (0.42) | ITGB2ICAM1ITGALKMT2AALDH1A1 | |
| SCHEMBL6217163 | 0.89 | ITGB2 (0.42) | ITGB2ICAM1ITGALKMT2AALDH1A1 | |
| SCHEMBL6219442 | 0.89 | ITGB2 (0.51) | ITGB2ICAM1ITGALKMT2AALDH1A1 | |
| SCHEMBL6216686 | 0.86 | ITGB2 (0.41) | ITGB2ICAM1ITGALKMT2AALDH1A1 | |
| SCHEMBL6220461 | 0.86 | KMT2A (0.44) | ITGB2ICAM1ITGALKMT2AALDH1A1 | |
| SCHEMBL6218734 | 0.86 | KMT2A (0.42) | ITGB2ICAM1ITGALKMT2AALDH1A1 | |
| SCHEMBL6219275 | 0.86 | ITGB2 (0.51) | ITGB2ICAM1ITGALKMT2AALDH1A1 | |
| SCHEMBL6217712 | 0.85 | KMT2A (0.43) | ITGB2ICAM1ITGALKMT2AALDH1A1 | |
| SCHEMBL6217240 | 0.85 | ITGB2 (0.42) | ITGB2ICAM1ITGALKMT2AALDH1A1 | |
| SCHEMBL6220457 | 0.84 | ITGB2 (0.41) | ITGB2ICAM1ITGALKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | claimed |