⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26655071 | 1.00 | — | — | |
| SCHEMBL52490 | 1.00 | — | — | |
| SCHEMBL23136777 | 1.00 | — | — | |
| SCHEMBL1895624 | 0.87 | ESR2 (0.45) | — | |
| SCHEMBL674422 | 0.86 | ESR1 (0.39) | — | |
| SCHEMBL674423 | 0.86 | ESR1 (0.39) | — | |
| SCHEMBL63504 | 0.86 | ESR1 (0.39) | — | |
| SCHEMBL6561164 | 0.86 | EPHX2 (0.39) | — | |
| SCHEMBL44806 | 0.86 | ESR1 (0.39) | — | |
| SCHEMBL5936418 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260137703-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECH LIMITED (GB) | 2026-05-21 | — | — | US | disclosed |
| US-20260001875-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREATMENT OF PARKINSON'S DISEASE | UNIV DUNDEE (GB) | 2026-01-01 | — | — | US | disclosed |
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| EP-4522603-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE | University Of Dundee (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119325470-A | Aminopyrimidinyl derivatives for the treatment of parkinson's disease | 邓迪大学 | 2025-01-17 | — | — | CN | disclosed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |
| WO-2023218187-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE | UNIVERSITY OF DUNDEE (GB) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023218187-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE | UNIVERSITY OF DUNDEE (GB) | 2023-11-16 | — | — | WO | disclosed |
| EP-4276097-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE | University Of Dundee (GB) | 2023-11-15 | — | — | EP | disclosed |
| EP-4276097-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE | University Of Dundee (GB) | 2023-11-15 | — | — | EP | disclosed |
| US-8088747-B2 | Analogue compounds of archaebacterial membrane lipids and liposomal compounds integrating such compounds | ECOLE NATIONALE SUPERIEURE DE CHIME DE RENNES (FR) | 2012-01-03 | — | — | US | disclosed |
| US-8088747-B2 | Analogue compounds of archaebacterial membrane lipids and liposomal compounds integrating such compounds | ECOLE NATIONALE SUPERIEURE DE CHIME DE RENNES (FR) | 2012-01-03 | — | — | US | disclosed |
| US-8088747-B2 | Analogue compounds of archaebacterial membrane lipids and liposomal compounds integrating such compounds | ECOLE NATIONALE SUPERIEURE DE CHIME DE RENNES (FR) | 2012-01-03 | — | — | US | disclosed |
| EP-1819824-B1 | COMPOUNDS ANALOGOUS TO LIPID MEMBRANES IN ARCHAEBACTERIA AND LIPOSOMAL COMPOSITIONS INCLUDING SAID COMPOUNDS | ENSCR (FR) | 2009-12-02 | — | — | EP | disclosed |
| EP-1819824-B1 | COMPOUNDS ANALOGOUS TO LIPID MEMBRANES IN ARCHAEBACTERIA AND LIPOSOMAL COMPOSITIONS INCLUDING SAID COMPOUNDS | ENSCR (FR) | 2009-12-02 | — | — | EP | disclosed |
| US-20090253677-A1 | HIV Integrase Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2009-10-08 | — | — | US | disclosed |
| US-20090232880-A1 | Analogue Compounds Of Archaebacterial Membrane Lipids And Liposomal Compounds Integrating Such Compounds | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2009-09-17 | — | — | US | disclosed |
| US-20090232880-A1 | Analogue Compounds Of Archaebacterial Membrane Lipids And Liposomal Compounds Integrating Such Compounds | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2009-09-17 | — | — | US | disclosed |
| US-20090232880-A1 | Analogue Compounds Of Archaebacterial Membrane Lipids And Liposomal Compounds Integrating Such Compounds | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2009-09-17 | — | — | US | disclosed |
| US-20090062383-A1 | Salts of Substituted Allophanates and Their Use in Drugs | GRUENENTHAL GMBH (DE) | 2009-03-05 | — | — | US | disclosed |