Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 11/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.39 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626167 | 1.00 | PSMB5 (0.58) | PSMB5FGFR1MEN1KMT2ANPC1 | |
| SCHEMBL13341572 | 0.89 | PSMB5 (0.49) | PSMB5FGFR1MEN1KMT2ANPC1 | |
| SCHEMBL610173 | 0.88 | PSMB5 (0.43) | PSMB5FGFR1MEN1KMT2ANPC1 | |
| SCHEMBL610174 | 0.88 | PSMB5 (0.43) | PSMB5FGFR1MEN1KMT2ANPC1 | |
| SCHEMBL608845 | 0.85 | FGFR1 (0.47) | PSMB5FGFR1MEN1KMT2ANPC1 | |
| SCHEMBL608846 | 0.85 | FGFR1 (0.47) | PSMB5FGFR1MEN1KMT2ANPC1 | |
| SCHEMBL10061375 | 0.84 | CCR6 (0.40) | PSMB5FGFR1MEN1KMT2ANPC1 | |
| Lysine SCHEMBL16061827 | 0.82 | FGFR1 (0.44) | PSMB5FGFR1MEN1KMT2ANPC1 | |
| SCHEMBL22349310 | 0.82 | MEN1 (0.56) | PSMB5MEN1KMT2ANPC1HPGD | |
| SCHEMBL17693091 | 0.81 | MEN1 (0.59) | PSMB5FGFR1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | L1CAM, LY96, GMFG | PSMB5 1264/4885FGFR1 4281/4885MEN1 4644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.