Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 7/20 | 1.00 |
| ▸ | CTSL | P07711 | 2/20 | 0.67 |
| ▸ | PTPN13 | Q12923 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260964 | 0.97 | PTPRC (1.00) | PTPRCCTSLPTPN13NPC1RAB9A | |
| SCHEMBL30571451 | 0.83 | PTPRC (0.74) | PTPRCCTSLPTPN13NPC1RAB9A | |
| SCHEMBL26567399 | 0.83 | PTPRC (0.74) | PTPRCCTSLPTPN13NPC1RAB9A | |
| SCHEMBL15855077 | 0.81 | PTPRC (0.69) | PTPRCCTSLPTPN13NPC1RAB9A | |
| SCHEMBL2601917 | 0.81 | PTPRC (0.68) | PTPRCCTSLPTPN13NPC1RAB9A | |
| SCHEMBL6262671 | 0.81 | PTPRC (1.00) | PTPRCCTSLPTPN13NPC1RAB9A | |
| SCHEMBL8197262 | 0.81 | PTPRC (0.71) | PTPRCCTSLPTPN13NPC1RAB9A | |
| SCHEMBL30572132 | 0.79 | PTPRC (0.69) | PTPRCCTSLPTPN13NPC1RAB9A | |
| SCHEMBL8201092 | 0.79 | PTPRC (0.65) | PTPRCCTSLPTPN13NPC1RAB9A | |
| SCHEMBL31725067 | 0.79 | PTPRC (0.65) | PTPRCCTSLPTPN13RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242363-B1 | CD45 INHIBITORS | ASTRAZENECA AB (SE) | 2005-11-02 | — | — | EP | disclosed |
| US-20030207812-A1 | Cd45 inhibitors | ASTRAZENECA AB (SE) | 2003-11-06 | — | — | US | disclosed |
| EP-1242363-A2 | CD45 INHIBITORS | AstraZeneca AB (SE) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001046125-A2 | CD45 INHIBITORS | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207812-A1 | Cd45 inhibitors | CD74, CD2, PTPRC | PTPRC 3/4885CTSL 2041/4885PTPN13 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.