Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17074946 | 0.82 | JAK2 (0.35) | — | |
| SCHEMBL1815743 | 0.79 | RARB (0.33) | RARBRARGRARA | |
| SCHEMBL16876916 | 0.69 | RARB (0.40) | RARBRARGRARA | |
| SCHEMBL6266843 | 0.68 | ATM (0.35) | — | |
| SCHEMBL23093250 | 0.68 | PARP10 (0.38) | — | |
| SCHEMBL6266260 | 0.68 | ITGAV (0.35) | — | |
| SCHEMBL30885033 | 0.67 | RARB (0.49) | RARBRARGRARA | |
| SCHEMBL6224511 | 0.67 | RARB (0.49) | RARBRARGRARA | |
| SCHEMBL6266262 | 0.65 | ITGAV (0.35) | — | |
| SCHEMBL31219658 | 0.64 | MARK3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592421-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | Pharmacia Corporation (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |