SCHEMBL6261983

SCHEMBL6261983

O=C(O)c1cc(OC(=O)c2ccc(C(=O)c3ccccc3)cc2)cc(OC(=O)c2ccc(C(=O)c3ccccc3)cc2)c1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 4/20 0.57
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
MAPT P10636 2/20 0.53
PARP10 Q53GL7 1/20 0.53
ELANE P08246 3/20 0.51
ALDH1A1 P00352 2/20 0.48
POLB P06746 1/20 0.47
AKR1C3 P42330 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ATM Q13315 1/20 0.47
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12649365 0.93 KMT2A (0.59) KMT2AMEN1TDP1MAPTPARP10
SCHEMBL28423662 0.89 KMT2A (0.59) KMT2AMEN1TDP1MAPTPARP10
SCHEMBL11199506 0.87 TP53 (0.50) SRD5A2KMT2AMEN1TDP1MAPT
SCHEMBL6264457 0.87 KMT2A (0.50) SRD5A2KMT2AMEN1TDP1MAPT
SCHEMBL6264503 0.85 TSHR (0.59) KMT2AMEN1TDP1MAPTPARP10
SCHEMBL2755026 0.85 KMT2A (0.68) KMT2AMEN1TDP1MAPTPARP10
SCHEMBL11276120 0.83 TP53 (0.50) SRD5A2KMT2AMEN1TDP1MAPT
SCHEMBL8206009 0.83 PARP10 (0.72) KMT2AMEN1TDP1MAPTPARP10
SCHEMBL27812147 0.82 TDP1 (0.61) SRD5A2KMT2AMEN1TDP1MAPT
SCHEMBL11202828 0.82 AKR1C3 (0.55) KMT2AMEN1TDP1MAPTAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1347027-B1 Pressure sensitive polyacrylate adhesive TESA AG (DE) 2005-11-09 EP disclosed
EP-1311554-B1 METHOD FOR PRODUCING ADHESIVE POLYACRYLATES USING MERCAPTO FUNCTIONAL PHOTOINITIATORS TESA AG (DE) 2004-11-03 EP disclosed
US-20040049972-A1 Method for producing adhesive polyacrylates using mercapto functional photoinitiators TESA AG (DE) 2004-03-18 US disclosed
EP-1347027-A2 Pressure sensitive polyacrylate adhesive tesa AG (DE) 2003-09-24 EP disclosed
EP-1311554-A1 METHOD FOR PRODUCING ADHESIVE POLYACRYLATES USING MERCAPTO FUNCTIONAL PHOTOINITIATORS Tesa AG (DE) 2003-05-21 EP disclosed
WO-2002014378-A1 METHOD FOR PRODUCING ADHESIVE POLYACRYLATES USING MERCAPTO FUNCTIONAL PHOTOINITIATORS TESA AG (DE) 2002-02-21 WO disclosed