SCHEMBL626280

SCHEMBL626280

O=C(O)c1ccc2nc(NC(=O)C(OC3CCCC3)c3ccc(S(=O)(=O)C4CC4)cc3)sc2c1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185229 0.94 GCK (0.66) GCK
SCHEMBL184553 0.90 GCK (0.68) GCK
SCHEMBL184554 0.90 GCK (0.68) GCK
SCHEMBL19921741 0.90 GCK (0.68) GCK
SCHEMBL185569 0.86 GCK (0.62) GCK
SCHEMBL624605 0.83 GCK (0.46) GCK
SCHEMBL184850 0.82 GCK (0.58) GCK
SCHEMBL184849 0.82 GCK (0.58) GCK
SCHEMBL184548 0.81 GCK (0.63) GCK
SCHEMBL10231818 0.80 GCK (0.45) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020357-A1 ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION ADVINUS THERAPEUTICS LTD. (IN) 2012-02-16 WO claimed
WO-2012020357-A1 ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION ADVINUS THERAPEUTICS LTD. (IN) 2012-02-16 WO disclosed