Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 9/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905078 | 1.00 | PTPN1 (0.57) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3907652 | 1.00 | PTPN1 (0.57) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3914646 | 0.90 | PTPN1 (0.68) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3906826 | 0.90 | PTPN1 (0.58) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3905250 | 0.90 | PTPN1 (0.68) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3908153 | 0.90 | PTPN1 (0.68) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3909235 | 0.88 | PTPN1 (0.69) | PTPN1PTPN2PTPRCCYP2C9 | |
| Hydrochloric Acid SCHEMBL3906442 | 0.87 | PTPN1 (0.68) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3907219 | 0.86 | PTPN1 (0.72) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3905438 | 0.86 | PTPN1 (0.73) | PTPN1PTPN2PTPRCCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |