Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6263620 | 0.96 | PTPN1 (0.48) | PTPN1PTPN2PTPRCCYP2C9TACR1 | |
| SCHEMBL6261763 | 0.94 | PTPN1 (0.44) | PTPN1PTPN2PTPRCCYP2C9SLC6A2 | |
| SCHEMBL3910292 | 0.92 | PTPN1 (0.57) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6269188 | 0.91 | PTPN1 (0.55) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3910937 | 0.91 | PTPN1 (0.51) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6267335 | 0.88 | PTPN1 (0.48) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6268229 | 0.88 | PTPN1 (0.51) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6268098 | 0.87 | PTPN1 (0.53) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6262467 | 0.87 | PTPN1 (0.45) | PTPN1PTPN2PTPRCCYP2C9TACR1 | |
| SCHEMBL6266127 | 0.87 | PTPN1 (0.52) | PTPN1PTPN2PTPRCCYP2C9SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |