Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202795 | 0.84 | MAOB (0.38) | TAAR1IDO1MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL16167413 | 0.83 | IDO1 (0.55) | TAAR1IDO1AGXTNPC1RAB9A | |
| SCHEMBL26033709 | 0.83 | IDO1 (0.55) | TAAR1IDO1AGXTNPC1RAB9A | |
| SCHEMBL167999 | 0.80 | TAAR1 (0.52) | TAAR1IDO1AGXTNPC1RAB9A | |
| SCHEMBL27858180 | 0.79 | TAAR1 (0.47) | TAAR1IDO1AGXTNPC1RAB9A | |
| SCHEMBL11536855 | 0.79 | TAAR1 (0.57) | TAAR1IDO1AGXTSLC6A3 | |
| SCHEMBL3634118 | 0.78 | TAAR1 (0.50) | TAAR1IDO1AGXTNPC1RAB9A | |
| SCHEMBL5257888 | 0.78 | TAAR1 (0.50) | TAAR1IDO1AGXTNPC1RAB9A | |
| SCHEMBL8212553 | 0.78 | TAAR1 (0.50) | TAAR1IDO1AGXTNPC1RAB9A | |
| SCHEMBL28362772 | 0.78 | TAAR1 (0.50) | TAAR1IDO1AGXTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103119031-A | Substituted amide compounds | ASTELLAS PHARMA INC | 2013-05-22 | — | — | CN | claimed |
| CN-113166139-A | Pyrrolo [2,3-b ] pyridines as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-103119031-B | Substituted amide compounds | ASTELLAS PHARMA INC | 2015-01-14 | — | — | CN | disclosed |
| CN-102548965-B | Substituted amide compounds | ASTELLAS PHARMA INC | 2014-04-09 | — | — | CN | disclosed |
| CN-103119031-A | Substituted amide compounds | ASTELLAS PHARMA INC | 2013-05-22 | — | — | CN | disclosed |
| CN-102548965-A | Substituted amide compounds | ASTELLAS PHARMA INC | 2012-07-04 | — | — | CN | disclosed |
| CN-102134214-A | Isoindolone compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA SWEDEN AB | 2011-07-27 | — | — | CN | disclosed |
| CN-101039907-B | Isoindolone compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA AB | 2011-02-23 | — | — | CN | disclosed |
| CN-101039907-A | Isoindolone compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | CN | disclosed |
| EP-0930296-B2 | FLUORINATED PROSTAGLANDIN DERIVATIVES AND MEDICINES | ASAHI GLASS CO LTD (JP) | 2005-11-02 | — | — | EP | disclosed |
| CN-1108289-C | Difluoroprostaglundin derivatives and their use | ASAHI GLASS CO LTD (JP) | 2003-05-14 | — | — | CN | disclosed |
| EP-0850926-B1 | Difluoroprostaglandin derivatives and their use | ASAHI GLASS CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| EP-0930296-B1 | FLUORINATED PROSTAGLANDIN DERIVATIVES AND MEDICINES | ASAHI GLASS CO LTD (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-5985920-A | COMPOUNDS FOR TREATMENT OF VISION DEFECTS SUCH AS GLAUCOMA | ASAHI GLASS COMPANY LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0930296-A1 | FLUORINATED PROSTAGLANDIN DERIVATIVES AND MEDICINES | ASAHI GLASS COMPANY LTD. (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5886035-A | PREVENTIVE AND THERAPEUTICAL MEDICINE FOR EYE DISEASE | ASAHI GLASS COMPANY LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| CN-1187486-A | Difluoroprostaglundin Derivatives and their use | ASAHI GLASS CO LTD (JP) | 1998-07-15 | — | — | CN | disclosed |
| EP-0850926-A2 | Difluoroprostaglandin derivatives and their use | ASAHI GLASS COMPANY LTD. (JP) | 1998-07-01 | — | — | EP | disclosed |