Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 16/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3910215 | 0.93 | PTPN1 (0.45) | PTPN1PTPN2 | |
| SCHEMBL3909144 | 0.88 | PTPN1 (0.45) | PTPN1PTPN2 | |
| SCHEMBL6264720 | 0.86 | PTPN1 (0.44) | PTPN1PTPN2 | |
| SCHEMBL3907463 | 0.86 | PTPN1 (0.43) | PTPN1PTPN2 | |
| SCHEMBL6262345 | 0.86 | PTPN1 (0.44) | PTPN1PTPN2 | |
| SCHEMBL3916526 | 0.86 | PTPN1 (0.44) | PTPN1PTPN2 | |
| SCHEMBL6263343 | 0.85 | PTPN1 (0.43) | PTPN1PTPN2 | |
| SCHEMBL6265993 | 0.85 | PTPN1 (0.43) | PTPN1PTPN2 | |
| SCHEMBL6265089 | 0.84 | PTPN1 (0.46) | PTPN1PTPN2 | |
| SCHEMBL6263584 | 0.84 | PTPN1 (0.58) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |