Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 19/20 | 0.47 |
| ▸ | INSR | P06213 | 7/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | TXK | P42681 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414238 | 1.00 | ITK (0.47) | ITKINSRSTING1TXK | |
| SCHEMBL6414426 | 0.93 | ITK (0.54) | ITKINSRTXK | |
| SCHEMBL6264380 | 0.89 | ITK (0.47) | ITKINSRTXK | |
| SCHEMBL6419603 | 0.89 | ITK (0.51) | ITKINSRTXK | |
| SCHEMBL6414243 | 0.89 | ITK (0.51) | ITKINSRTXK | |
| SCHEMBL6414434 | 0.81 | ITK (0.53) | ITKINSRTXK | |
| SCHEMBL6416855 | 0.81 | STING1 (0.42) | ITKINSRSTING1TXK | |
| SCHEMBL6416849 | 0.81 | STING1 (0.42) | ITKINSRSTING1TXK | |
| SCHEMBL6419607 | 0.79 | ITK (0.50) | ITKINSRTXK | |
| SCHEMBL6273363 | 0.77 | ITK (0.56) | ITKINSRTXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209284-A1 | Tec kinase inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | US | disclosed |
| WO-2005079791-A1 | THIOPHENE -2- CARBOXYLIC ACID - (1H - BENZIMIDAZOL - 2 YL) - AMIDE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF THE TEC KINASE ITK (INTERLEUKIN -2- INDUCIBLE T CELL KINASE) FOR THE TREATMENT OF INFLAMMATION, IMMUNOLOGICAL AND ALLERGIC DISORDERS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209284-A1 | Tec kinase inhibitors | TEC, ITK, TXK | ITK 2/4885INSR 910/4885STING1 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.