Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 19/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267851 | 0.95 | PTPN1 (0.51) | PTPN1PTPN2PTPRCCYP2C9TACR1 | |
| SCHEMBL6264577 | 0.95 | PTPN1 (0.52) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3904625 | 0.94 | PTPN1 (0.57) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6262139 | 0.93 | PTPN1 (0.45) | PTPN1PTPN2PTPRCCYP2C9TACR1 | |
| SCHEMBL6263477 | 0.92 | PTPN1 (0.49) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3913813 | 0.91 | PTPN1 (0.50) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6267531 | 0.91 | PTPN1 (0.48) | PTPN1PTPN2PTPRCCYP2C9TACR1 | |
| SCHEMBL6269454 | 0.90 | PTPN1 (0.50) | PTPN1PTPN2 | |
| SCHEMBL6265798 | 0.90 | PTPN1 (0.49) | PTPN1PTPN2PTPRCCYP2C9TACR1 | |
| SCHEMBL6264924 | 0.89 | PTPN1 (0.48) | PTPN1PTPN2PTPRCCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |