Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 19/20 | 0.68 |
| ▸ | PTPN2 | P17706 | 11/20 | 0.59 |
| ▸ | PTPRC | P08575 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264807 | 0.92 | PTPN1 (0.68) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6268303 | 0.92 | PTPN1 (0.68) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6262187 | 0.90 | PTPN1 (0.68) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3907244 | 0.89 | PTPN1 (0.84) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6268306 | 0.87 | PTPN1 (0.68) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3919927 | 0.84 | PTPN1 (0.84) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6262362 | 0.84 | PTPN1 (0.65) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6266282 | 0.84 | PTPN1 (0.60) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3904547 | 0.84 | PTPN1 (0.85) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6267983 | 0.83 | PTPN1 (0.59) | PTPN1PTPN2PTPRCCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |