Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 10/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533244 | 0.92 | PTPN1 (0.49) | PTPN1PTPN2 | |
| SCHEMBL6265776 | 0.92 | PTPN1 (0.40) | PTPN1PTPN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6266854 | 0.90 | PTPN1 (0.46) | PTPN1PTPN2 | |
| SCHEMBL6263421 | 0.89 | PTPN1 (0.49) | PTPN1PTPN2 | |
| SCHEMBL6264921 | 0.89 | PTPN1 (0.45) | PTPN1PTPN2 | |
| SCHEMBL3912232 | 0.87 | PTPN1 (0.46) | PTPN1PTPN2 | |
| SCHEMBL6264927 | 0.86 | PTPN1 (0.43) | PTPN1PTPN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6263509 | 0.85 | PTPN1 (0.56) | PTPN1PTPN2 | |
| SCHEMBL6280774 | 0.85 | PTPN1 (0.40) | PTPN1PTPN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6264478 | 0.85 | PTPN1 (0.54) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |