Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185835 | 0.89 | KDM4E (0.46) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL3307573 | 0.83 | — | — | |
| SCHEMBL9459746 | 0.83 | — | — | |
| SCHEMBL9459911 | 0.83 | — | — | |
| SCHEMBL25067255 | 0.82 | KDM4E (0.45) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL571582 | 0.82 | CYP17A1 (0.47) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL17598731 | 0.82 | CYP17A1 (0.47) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL27742029 | 0.82 | CYP17A1 (0.47) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL4950866 | 0.80 | KDM4E (0.44) | KDM4EKMT2ACYP19A1CYP17A1 | |
| SCHEMBL14420588 | 0.80 | KDM4E (0.44) | KDM4EKMT2ACYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107427758-A | Utilize the separation of ion liquid solvent | 切弗朗菲利浦化学公司 | 2017-12-01 | — | — | CN | claimed |
| EP-1000620-B1 | Lp(a)-LOWERING AGENTS AND APOPROTEIN (a) PRODUCTION INHIBITORS | TAIHO PHARMACEUTICAL CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6166036-A | Lp(a)-lowering agent and apolipoprotein (a) formation suppressing agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-1000620-A1 | Lp(a)-LOWERING AGENTS AND APOPROTEIN (a) PRODUCTION INHIBTORS | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5145865-A | Fatty acid, cholesterol synthesis inhibitors; enzyme inhibitors; antilipemic agents | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |