Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.64 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907472 | 0.91 | PTPN1 (0.77) | PTPN1PTPRCPTPN2FFAR1 | |
| SCHEMBL3907610 | 0.90 | PTPN1 (0.65) | PTPN1PTPRCPTPN2 | |
| SCHEMBL6268054 | 0.89 | PTPN1 (0.59) | PTPN1PTPRCPTPN2 | |
| SCHEMBL6262486 | 0.88 | PTPN1 (0.64) | PTPN1PTPRCPTPN2NR1H4FFAR1 | |
| SCHEMBL6268410 | 0.88 | PTPN1 (0.83) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3907645 | 0.86 | PTPN1 (0.76) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3909638 | 0.85 | PTPN1 (0.66) | PTPN1 | |
| SCHEMBL3907751 | 0.84 | PTPN1 (0.60) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3909147 | 0.84 | PTPN1 (0.65) | PTPN1PTPRCPTPN2FFAR1 | |
| SCHEMBL3910993 | 0.84 | PTPN1 (0.56) | PTPN1PTPRCPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |