Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.69 |
| ▸ | PTPN2 | P17706 | 11/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265498 | 0.92 | PTPN1 (0.70) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6263306 | 0.91 | PTPN1 (0.78) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3909302 | 0.88 | PTPN1 (0.86) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6263312 | 0.85 | PTPN1 (0.79) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6267294 | 0.84 | PTPN1 (0.64) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3913254 | 0.82 | PTPN1 (0.86) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3903775 | 0.82 | PTPN1 (1.00) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6264526 | 0.82 | PTPN1 (0.61) | PTPN1 | |
| SCHEMBL6264650 | 0.78 | PTPN1 (0.69) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6275172 | 0.78 | PTPN1 (0.58) | PTPN1PTPN2PTPRCCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |