Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.67 |
| ▸ | ARG2 | P78540 | 4/20 | 0.46 |
| ▸ | ARG1 | P05089 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ornithine Aketoglutarate SCHEMBL6265607 | 1.00 | GSR (0.67) | GSRARG2ARG1CYP1A2CYP2C19 | |
| Lysine SCHEMBL10450567 | 0.94 | GSR (0.77) | GSRARG2ARG1CYP1A2CYP2C19 | |
| Lysine SCHEMBL7446194 | 0.94 | GSR (0.77) | GSRARG2ARG1CYP1A2CYP2C19 | |
| Lysine SCHEMBL30642406 | 0.94 | GSR (0.77) | GSRARG2ARG1CYP1A2CYP2C19 | |
| Lysine SCHEMBL31374697 | 0.94 | GSR (0.77) | GSRARG2ARG1CYP1A2CYP2C19 | |
| Lysine SCHEMBL8138033 | 0.94 | GSR (0.77) | GSRARG2ARG1CYP1A2CYP2C19 | |
| Lysine SCHEMBL27638789 | 0.89 | GSR (0.69) | GSRARG2ARG1CYP1A2CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL28537927 | 0.88 | GSR (0.54) | GSRCYP1A2NOS2GRM8GRM6 | |
| D-Ornithine SCHEMBL1537220 | 0.87 | GSR (0.86) | GSRARG2ARG1CYP1A2CYP2C19 | |
| D-Ornithine SCHEMBL43724 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472987-B1 | Antimicrobial peptides active against plant pathogens, their use and screening methods pertaining thereto | VIRTUAL DRUG DEV INC (US) | 2005-11-02 | — | — | EP | disclosed |
| EP-0919566-A2 | Antimicrobial peptides and their use against plant pathogens | ENICHEM S.p.A. (IT) | 1999-06-02 | — | — | EP | disclosed |
| US-5519115-A | BACTERICIDES OR FUNGICIDES | ENICHEM S.P.A. (IT) | 1996-05-21 | — | — | US | disclosed |
| US-5424395-A | Magainins | ENICHEM S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| EP-0497366-A2 | Antimicrobial peptides and their use against plant pathogens | ENICHEM S.p.A. (IT) | 1992-08-05 | — | — | EP | disclosed |
| EP-0472987-A1 | Antimicrobial peptides active against plant pathogens, their use and screening methods pertaining thereto | ENICHEM S.p.A. (IT) | 1992-03-04 | — | — | EP | disclosed |