Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 14/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908002 | 0.90 | PTPN1 (0.83) | PTPN1 | |
| Acetic Acid SCHEMBL6265652 | 0.87 | PTPN1 (0.79) | PTPN1 | |
| SCHEMBL3907459 | 0.81 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL3909575 | 0.81 | PTPN1 (0.82) | PTPN1 | |
| SCHEMBL3910911 | 0.78 | PTPN1 (0.66) | PTPN1MEN1POLBKMT2A | |
| SCHEMBL3907306 | 0.77 | PTPN1 (0.84) | PTPN1 | |
| SCHEMBL3913254 | 0.76 | PTPN1 (0.86) | PTPN1 | |
| SCHEMBL3911886 | 0.74 | PTPN1 (0.81) | PTPN1 | |
| SCHEMBL6264534 | 0.73 | PTPN1 (0.61) | PTPN1MEN1POLBKMT2A | |
| SCHEMBL6264526 | 0.73 | PTPN1 (0.61) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |