Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265768 | 1.00 | PPARG (0.41) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL5429179 | 0.92 | PPARG (0.40) | PPARGPPARALMNABCL2MTNR1A | |
| SCHEMBL5429174 | 0.92 | PPARG (0.40) | PPARGPPARALMNABCL2MTNR1A | |
| SCHEMBL5432570 | 0.84 | S1PR1 (0.45) | PPARGPPARALMNAMAPTSMN1; SMN2 | |
| SCHEMBL5432566 | 0.84 | S1PR1 (0.45) | PPARGPPARALMNAMAPTSMN1; SMN2 | |
| SCHEMBL5427399 | 0.83 | PPARA (0.46) | PPARGPPARAPPARDNR1H4PTPN11 | |
| SCHEMBL5427391 | 0.83 | PPARA (0.46) | PPARGPPARAPPARDNR1H4PTPN11 | |
| SCHEMBL5414627 | 0.81 | PPARG (0.51) | PPARGPPARAPPARDNR1H3PTPN11 | |
| SCHEMBL5427796 | 0.81 | PPARG (0.51) | PPARGPPARAPPARDNR1H3PTPN11 | |
| SCHEMBL5414621 | 0.81 | PPARG (0.51) | PPARGPPARAPPARDNR1H3PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602642-A1 | IMINO ETHER DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-12-07 | — | — | EP | disclosed |