SCHEMBL6266345

SCHEMBL6266345

O=Cc1ccc(-c2ccc(CCNC(=O)OC[C@H](O)c3cccc(Cl)c3)cc2)s1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 20/20 0.55
ADRB1 P08588 17/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6244075 0.76 ADRB3 (0.55) ADRB3ADRB1
SCHEMBL4474254 0.76 ADRB3 (0.52) ADRB3ADRB1
SCHEMBL4474256 0.76 ADRB3 (0.52) ADRB3ADRB1
SCHEMBL6266344 0.74 ADRB3 (0.42) ADRB3ADRB1
SCHEMBL6266343 0.73 ADRB3 (0.45) ADRB3ADRB1
SCHEMBL6239350 0.73 ADRB3 (0.45) ADRB3ADRB1
Hydrochloric Acid SCHEMBL4479851 0.71 ADRB3 (0.98) ADRB3ADRB1
Hydrochloric Acid SCHEMBL4479860 0.71 ADRB3 (0.98) ADRB3ADRB1
SCHEMBL6239352 0.67 ADRB3 (0.42) ADRB3ADRB1
SCHEMBL2217723 0.66 IKBKB (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1546086-A2 AMINOALCOHOL DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2005-06-29 EP disclosed
WO-2004002939-A2 AMINOALCOHOL DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-01-08 WO disclosed