Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.83 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 3/20 | 0.33 |
| ▸ | GABRD | O14764 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL1933771 | 0.97 | SLC7A5 (0.79) | SLC7A5SLC1A3SLC1A2SLC1A1LMNA | |
| Valine SCHEMBL15602719 | 0.92 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1LMNA | |
| Valine SCHEMBL482773 | 0.92 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1LMNA | |
| Valine SCHEMBL27571970 | 0.92 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1LMNA | |
| Valine SCHEMBL288203 | 0.91 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL43678 | 0.91 | — | — | |
| Valine SCHEMBL1813972 | 0.91 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL8516 | 0.91 | — | — | |
| Valine SCHEMBL41225 | 0.91 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL8515 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101519378-B | Diaryl pyrimidyl guanidine and preparation method and pharmaceutical use of same | UNIV SHANXI NORMAL | 2011-07-20 | — | — | CN | claimed |
| CN-114989034-B | Synthesis method of iohexol impurity | 浙江海洲制药股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-116200290-A | Lactobacillus paracasei capable of inhibiting proliferation of colorectal cancer cells and application thereof | 上海承葛医药科技有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-114989034-A | Synthesis method of iohexol impurity | 浙江海洲制药有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-112457426-B | Method for simultaneously extracting different lycium barbarum polysaccharide components | 中国科学院兰州化学物理研究所 | 2022-01-28 | — | — | CN | disclosed |
| WO-2021111588-A1 | PRETREATMENT METHOD | 日本電信電話株式会社 | 2021-06-10 | — | — | WO | disclosed |
| CN-112724276-A | Ultrasonic-assisted extraction process for optimizing aralia leucotaxis stem bark polysaccharide based on response surface method | 昭通学院 | 2021-04-30 | — | — | CN | disclosed |
| CN-112457426-A | Method for simultaneously extracting different lycium barbarum polysaccharide components | 中国科学院兰州化学物理研究所 | 2021-03-09 | — | — | CN | disclosed |
| CN-107841478-B | Bacillus strain for efficient broad-spectrum decoloration and degradation of active dye and application thereof | 黄冈师范学院 | 2020-05-12 | — | — | CN | disclosed |
| CN-102282172-B | Anti-extended type I glycosphingolipid antibody, derivative and use thereof | GLYCONEX INC | 2014-02-19 | — | — | CN | disclosed |
| CN-102282172-A | Anti-extended type I glycosphingolipid antibody, derivative and use thereof | — | 2011-12-14 | — | — | CN | disclosed |
| CN-1232639-C | Gamma-tocopherol tranferase, gene and use thereof | CHINESE ACAD INST MICROBIOLOGY (CN) | 2005-12-21 | — | — | CN | disclosed |
| EP-1009447-B1 | HYDROXYMETHYL PHOSPHINE COMPOUNDS FOR USE AS DIAGNOSTIC AND THERAPEUTIC PHARMACEUTICALS AND METHOD OF MAKING SAME | UNIV MISSOURI (US) | 2005-08-10 | — | — | EP | disclosed |
| CN-1510132-A | Gamma-tocopherol tranferase, gene and use thereof | 中国科学院微生物研究所 | 2004-07-07 | — | — | CN | disclosed |
| EP-1009447-A4 | HYDROXYMETHYL PHOSPHINE COMPOUNDS FOR USE AS DIAGNOSTIC AND THERAPEUTIC PHARMACEUTICALS AND METHOD OF MAKING SAME | UNIV MISSOURI (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-1009447-A1 | HYDROXYMETHYL PHOSPHINE COMPOUNDS FOR USE AS DIAGNOSTIC AND THERAPEUTIC PHARMACEUTICALS AND METHOD OF MAKING SAME | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2000-06-21 | — | — | EP | disclosed |
| US-6054115-A | PURIFYING BY EXPOSING A MIXTURE OF UNCOORDINATED HYDROXYALKYL PHOSPHINE GROUPS AND COORDINATED HYDROXYALKYL PHOSPHINE GROUPS TO AN AMINE TO SEPARATE THE UNBOUND COORDINATED GROUPS FROM THE BOUND UNCOORDINATED GROUPS | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2000-04-25 | — | — | US | disclosed |
| US-5855867-A | RADIOLOGICAL IMAGING | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1999-01-05 | — | — | US | disclosed |
| WO-1998041242-A1 | HYDROXYMETHYL PHOSPHINE COMPOUNDS FOR USE AS DIAGNOSTIC AND THERAPEUTIC PHARMACEUTICALS AND METHOD OF MAKING SAME | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1998-09-24 | — | — | WO | disclosed |