Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 16/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 8/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6263443 | 0.93 | PTPN1 (0.40) | PTPN1PTPN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6265089 | 0.92 | PTPN1 (0.46) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6267161 | 0.92 | PTPN1 (0.56) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6262345 | 0.90 | PTPN1 (0.44) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6265776 | 0.90 | PTPN1 (0.40) | PTPN1PTPN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6262198 | 0.90 | PTPN1 (0.41) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6262095 | 0.89 | PTPN1 (0.39) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3909144 | 0.89 | PTPN1 (0.45) | PTPN1PTPN2 | |
| SCHEMBL6262829 | 0.89 | PTPN1 (0.41) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6267160 | 0.89 | PTPN1 (0.40) | PTPN1PTPN2PTPRCCYP2C9SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |