SCHEMBL6268992

SCHEMBL6268992

Nc1ccn(CCC(O)O)c(=O)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 2/20 0.46
SLC22A6 Q4U2R8 1/20 0.45
EP300 Q09472 9/20 0.38
MAPT P10636 3/20 0.37
LMNA P02545 3/20 0.37
THRB P10828 1/20 0.37
MTOR P42345 1/20 0.37
MDM2 Q00987 1/20 0.37
NCOA1 Q15788 1/20 0.37
NCOA3 Q9Y6Q9 1/20 0.37
PDE3A Q14432 3/20 0.35
CACNA1F O60840 2/20 0.35
ALB P02768 2/20 0.35
CACNA1D Q01668 2/20 0.35
CACNA1S Q13698 2/20 0.35
CACNA1C Q13936 2/20 0.35
NT5E P21589 1/20 0.35
CYP2D6 P10635 1/20 0.35
DNMT1 P26358 1/20 0.35
HDAC1 Q13547 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3680116 0.81 FGFR1 (0.52) FGFR1SLC22A6EP300MAPTLMNA
SCHEMBL23343373 0.80 FGFR1 (0.44) FGFR1SLC22A6EP300MAPTLMNA
SCHEMBL2152988 0.79 FGFR1 (0.41) FGFR1SLC22A6EP300MAPTCYP2D6
SCHEMBL6379845 0.79 FGFR1 (0.43) FGFR1SLC22A6EP300MAPTLMNA
SCHEMBL22666358 0.78 FGFR1 (0.42) FGFR1SLC22A6EP300MAPT
SCHEMBL12261276 0.78 FGFR1 (0.47) FGFR1SLC22A6EP300MAPTLMNA
SCHEMBL9569565 0.78 FGFR1 (0.46) FGFR1SLC22A6EP300MAPTNT5E
SCHEMBL9569548 0.78 FGFR1 (0.46) FGFR1SLC22A6EP300MAPTNT5E
SCHEMBL9569539 0.78 FGFR1 (0.46) FGFR1SLC22A6EP300MAPTNT5E
SCHEMBL22078831 0.77 FGFR1 (0.43) FGFR1SLC22A6EP300MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005087788-A2 METHODS FOR PREPARATION OF NUCLEOSIDE PHOSPHONATE ESTERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-09-22 WO disclosed