Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.31 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270623 | 0.94 | PTGER4 (0.38) | PTGER4ADRB3CCR5CA2IDH2 | |
| SCHEMBL6804273 | 0.92 | PTGER4 (0.34) | PTGER4ADRB3CCR5IDH2 | |
| SCHEMBL6804277 | 0.92 | PTGER4 (0.34) | PTGER4ADRB3CCR5IDH2 | |
| SCHEMBL6802975 | 0.88 | PTGER4 (0.37) | PTGER4ADRB3CCR5CA2IDH2 | |
| SCHEMBL6809306 | 0.88 | PTGER4 (0.34) | PTGER4ADRB3CCR5CA2IDH2 | |
| SCHEMBL6809311 | 0.88 | PTGER4 (0.34) | PTGER4ADRB3CCR5CA2IDH2 | |
| SCHEMBL6802969 | 0.88 | PTGER4 (0.37) | PTGER4ADRB3CCR5CA2IDH2 | |
| SCHEMBL6680691 | 0.88 | PTGER4 (0.37) | PTGER4ADRB3CCR5CA2FKBP1A | |
| SCHEMBL6804698 | 0.88 | PTGER4 (0.37) | PTGER4ADRB3CCR5CA2FKBP1A | |
| SCHEMBL6804860 | 0.86 | PTGER4 (0.33) | PTGER4ADRB3CCR5IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |