Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269783 | 1.00 | MEN1 (0.36) | MEN1KMT2ATP53HSP90AA1KCNH2 | |
| SCHEMBL6274196 | 0.93 | LRRK2 (0.37) | MEN1KMT2AHSP90AA1LRRK2L3MBTL1 | |
| SCHEMBL6272461 | 0.93 | PTPN2 (0.40) | MEN1KMT2AKCNH2LRRK2L3MBTL1 | |
| SCHEMBL6272463 | 0.93 | PTPN2 (0.40) | MEN1KMT2AKCNH2LRRK2L3MBTL1 | |
| SCHEMBL6274200 | 0.93 | LRRK2 (0.37) | MEN1KMT2AHSP90AA1LRRK2L3MBTL1 | |
| SCHEMBL6271198 | 0.90 | KMT2A (0.38) | MEN1KMT2AKCNH2LRRK2L3MBTL1 | |
| SCHEMBL6271201 | 0.90 | KMT2A (0.38) | MEN1KMT2AKCNH2LRRK2L3MBTL1 | |
| SCHEMBL6269051 | 0.90 | LRRK2 (0.39) | MEN1KMT2AKCNH2LRRK2L3MBTL1 | |
| SCHEMBL6269043 | 0.90 | LRRK2 (0.39) | MEN1KMT2AKCNH2LRRK2L3MBTL1 | |
| SCHEMBL6272709 | 0.89 | LRRK2 (0.40) | MEN1KMT2AKCNH2LRRK2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |