SCHEMBL6270149

SCHEMBL6270149

CC(=O)OCC(I)CC(F)(Cl)C(F)(F)Cl

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL773827 0.79 TDP1 (0.43) TDP1ALDH1A1LMNAHSD17B10
SCHEMBL7567947 0.79 TDP1 (0.39) TDP1ALDH1A1LMNAHSD17B10
SCHEMBL799024 0.77 TDP1 (0.38) TDP1ALDH1A1LMNAHSD17B10
SCHEMBL28460333 0.75 TDP1 (0.36) TDP1
SCHEMBL28446773 0.73 TDP1 (0.35) TDP1
SCHEMBL12246481 0.71
SCHEMBL30193522 0.70 TDP1 (0.33) TDP1
SCHEMBL6268854 0.69 MEN1 (0.31) TDP1LMNA
SCHEMBL22783224 0.69 TDP1 (0.47) TDP1ALDH1A1LMNAHSD17B10
SCHEMBL6813085 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1603959-A1 FUNCTIONALIZED FLUOROMONOMERS AND THEIR COPOLYMERS WITH VINYLIDENE FLUORIDE SOLVAY (Société Anonyme) (BE) 2005-12-14 EP claimed
WO-2004081066-A1 FUNCTIONALIZED FLUOROMONOMERS AND THEIR COPOLYMERS WITH VINYLIDENE FLUORIDE Solvay (Société Anonyme) (BE) 2004-09-23 WO claimed
EP-1603959-A1 FUNCTIONALIZED FLUOROMONOMERS AND THEIR COPOLYMERS WITH VINYLIDENE FLUORIDE SOLVAY (Société Anonyme) (BE) 2005-12-14 EP disclosed
WO-2004081066-A1 FUNCTIONALIZED FLUOROMONOMERS AND THEIR COPOLYMERS WITH VINYLIDENE FLUORIDE Solvay (Société Anonyme) (BE) 2004-09-23 WO disclosed