Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268314 | 0.86 | SMN1; SMN2 (0.42) | BCHESMN1; SMN2LMNAGAAALDH1A1 | |
| SCHEMBL6268319 | 0.85 | GAA (0.31) | SMN1; SMN2GAA | |
| SCHEMBL6268517 | 0.82 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL6271775 | 0.82 | BCHE (0.31) | BCHE | |
| SCHEMBL5582045 | 0.77 | SMN1; SMN2 (0.33) | BCHESMN1; SMN2GAAALDH1A1 | |
| SCHEMBL5871323 | 0.73 | — | — | |
| SCHEMBL6267871 | 0.69 | KMT2A (0.31) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28336872 | 0.67 | BCHE (0.50) | BCHESMN1; SMN2LMNAGAAKDM2B | |
| Urea SCHEMBL28287663 | 0.66 | CA1 (0.31) | — | |
| SCHEMBL4171042 | 0.65 | CA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988059-B1 | HUMAN QUINONE REDUCTASE 2 CONJUGATES FOR ADEPT AND GDEPT | ENZACTA R & D LTD (GB) | 2005-12-07 | — | — | EP | disclosed |
| EP-1468698-A2 | HUMAN QUINONE REDUCTASE 2 CONJUGATES FOR ADEPT AND GDEPT | ENZACTA R & D LIMITED (GB) | 2004-10-20 | — | — | EP | disclosed |