⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3754904 | 0.74 | — | — | |
| SCHEMBL14343309 | 0.74 | DPP4 (0.33) | — | |
| SCHEMBL14343223 | 0.74 | DPP4 (0.33) | — | |
| SCHEMBL2387150 | 0.74 | — | — | |
| SCHEMBL9585978 | 0.74 | DPP4 (0.33) | — | |
| SCHEMBL293934 | 0.62 | — | — | |
| SCHEMBL4279010 | 0.61 | SLC18A3 (0.35) | — | |
| SCHEMBL30839632 | 0.60 | — | — | |
| SCHEMBL12104997 | 0.58 | — | — | |
| SCHEMBL3198068 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180160-B1 | ANTIBIOTIC-BASED GENE REGULATION SYSTEM | FUSSENEGGER MARTIN (CH) | 2005-06-15 | — | — | EP | disclosed |
| EP-1180160-A4 | ANTIBIOTIC-BASED GENE REGULATION SYSTEM | FUSSENEGGER MARTIN (CH) | 2002-10-09 | — | — | EP | disclosed |
| WO-2002033104-A2 | ANTIBIOTIC-BASED GENE REGULATION SYSTEM | CISTRONICS CELL TECHNOLOGY GMBH (CH) | 2002-04-25 | — | — | WO | disclosed |
| EP-1180160-A1 | ANTIBIOTIC-BASED GENE REGULATION SYSTEM | Fussenegger, Martin (CH) | 2002-02-20 | — | — | EP | disclosed |
| US-6287813-B1 | HOST CELL HAS NUCLEOTIDE SEQUENCE LINKED TO EUKARYOTIC PROMOTER AND PABR SEQUENCE, AND ALSO NUCLEIC ACID CODING FOR POLYPEPTIDE THAT BINDS TO SEQUENCE IN ABSENCE OF ANTIBIOTIC; PROTEIN PRODUCTION, TISSUE ENGINEERING, GENE THERAPY | CISTRONICS CELL TECHNOLOGY GMBH (CH) | 2001-09-11 | — | — | US | disclosed |
| WO-2000065080-A1 | ANTIBIOTIC-BASED GENE REGULATION SYSTEM | FUSSENEGGER, MARTIN (CH) | 2000-11-02 | — | — | WO | disclosed |