Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.65 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272436 | 1.00 | PPARG (0.65) | PPARGPPARAS1PR1PLA2G4BPPARD | |
| SCHEMBL5427478 | 0.90 | PPARG (0.53) | PPARGPPARAS1PR1PLA2G4BPPARD | |
| SCHEMBL5427475 | 0.90 | PPARG (0.53) | PPARGPPARAS1PR1PLA2G4BPPARD | |
| SCHEMBL5418691 | 0.89 | PPARG (0.54) | PPARGPPARAPLA2G4BPPARDPTPN11 | |
| SCHEMBL5418686 | 0.89 | PPARG (0.54) | PPARGPPARAPLA2G4BPPARDPTPN11 | |
| SCHEMBL5414627 | 0.87 | PPARG (0.51) | PPARGPPARAPLA2G4BPPARDPTPN11 | |
| SCHEMBL5414621 | 0.87 | PPARG (0.51) | PPARGPPARAPLA2G4BPPARDPTPN11 | |
| SCHEMBL5427796 | 0.87 | PPARG (0.51) | PPARGPPARAPLA2G4BPPARDPTPN11 | |
| SCHEMBL5423766 | 0.85 | PPARG (0.49) | PPARGPPARAPLA2G4BPPARDPTPN11 | |
| SCHEMBL5421008 | 0.85 | PPARG (0.49) | PPARGPPARAPLA2G4BPPARDPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602642-A1 | IMINO ETHER DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-12-07 | — | — | EP | disclosed |