Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.75 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.49 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5097082 | 1.00 | DPP4 (0.75) | DPP4DPP8DPP9FAP | |
| SCHEMBL5096978 | 1.00 | DPP4 (0.75) | DPP4DPP8DPP9FAP | |
| SCHEMBL5104097 | 0.91 | DPP4 (0.71) | DPP4DPP8DPP9FAP | |
| SCHEMBL5110073 | 0.91 | DPP4 (0.82) | DPP4DPP8DPP9 | |
| SCHEMBL5111135 | 0.91 | DPP4 (0.86) | DPP4DPP8DPP9 | |
| SCHEMBL5103695 | 0.90 | DPP4 (0.86) | DPP4DPP8DPP9FAP | |
| SCHEMBL5103924 | 0.88 | DPP4 (0.77) | DPP4DPP8DPP9 | |
| SCHEMBL6593506 | 0.86 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL6704487 | 0.85 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5103896 | 0.82 | DPP4 (0.69) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1598350-A1 | Pyrrolidines and thiazolidines derivatives, their preparation and their use in the treatment of hyperglycaemia and of type II Diabetis | LES LABORATOIRES SERVIER (FR) | 2005-11-23 | — | — | EP | disclosed |