SCHEMBL6273047

SCHEMBL6273047

OC[C@H]1O[C@@H](O)[C@H](Oc2cn(Cl)c3ccccc23)[C@@H](O)[C@H]1O

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.40
SLC5A2 P31639 9/20 0.40
SLC5A1 P13866 2/20 0.40
EPHX2 P34913 1/20 0.37
CD209 Q9NNX6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22492210 1.00 ATM (0.40) ATMSLC5A2SLC5A1EPHX2CD209
SCHEMBL5333550 1.00 ATM (0.40) ATMSLC5A2SLC5A1EPHX2CD209
SCHEMBL14892463 0.86 ATM (0.40) ATMSLC5A2SLC5A1EPHX2CD209
SCHEMBL3648218 0.86 SLC5A2 (0.42) ATMSLC5A2SLC5A1EPHX2
SCHEMBL22412720 0.86 SLC5A2 (0.42) ATMSLC5A2SLC5A1EPHX2
SCHEMBL154170 0.85 ATM (0.40) ATMSLC5A2SLC5A1EPHX2
SCHEMBL5032807 0.78 SLC5A2 (0.49) ATMSLC5A2SLC5A1EPHX2CD209
SCHEMBL14975385 0.78 SLC5A2 (0.49) ATMSLC5A2SLC5A1EPHX2CD209
SCHEMBL153497 0.78 MAPK8 (0.41) SLC5A2
SCHEMBL153201 0.78 SLC5A2 (0.37) ATMSLC5A2SLC5A1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2742359-A1 NEW METHOD AND KIT FOR PREDICTION SUCCESS OF IN VITRO FERTILIZATION Erasmus University Medical Center Rotterdam (NL) 2014-06-18 EP disclosed
WO-2013025095-A1 NEW METHOD AND KIT FOR PREDICTION SUCCESS OF IN VITRO FERTILIZATION ERASMUS UNIVERSITY MEDICAL CENTRE ROTTERDAM (NL) 2013-02-21 WO disclosed
WO-2005106001-A1 METHODS AND COMPOSITIONS FOR PLANT TRANSFORMATION PURDUE RESEARCH FOUNDATION (US) 2005-11-10 WO disclosed
EP-1325139-A1 BACTERIAL STRAINS, GENES AND ENZYMES FOR CONTROL OF BACTERIAL DISEASES BY QUENCHING QUORUM-SENSING SIGNALS Institute of Molecular Agrobiology (SG) 2003-07-09 EP disclosed
WO-2002016623-A1 BACTERIAL STRAINS, GENES AND ENZYMES FOR CONTROL OF BACTERIAL DISEASES BY QUENCHING QUORUM-SENSING SIGNALS INSTITUTE OF MOLECULAR AGROBIOLOGY (SG) 2002-02-28 WO disclosed
EP-0404576-A2 Recombinant avipoxvirus NIPPON ZEON CO., LTD. (JP) 1990-12-27 EP disclosed
US-4952502-A Carbomycin biosynthetic gene, designated carG, for use in streptomyces and other organisms ELI LILLY AND COMPANY (US) 1990-08-28 US disclosed
EP-0324647-A2 Vector for the expression of fusion proteins and protein immunogens MERCK & CO. INC. (US) 1989-07-19 EP disclosed
EP-0284205-A2 Carbomycin biosynthetic gene, designated carG, for use in streptomyces and other organisms ELI LILLY AND COMPANY (US) 1988-09-28 EP disclosed