Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690541 | 0.83 | — | — | |
| SCHEMBL18632223 | 0.78 | CA1 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL510834 | 0.76 | CA1 (0.36) | CA12CA1CA2CA9 | |
| SCHEMBL20515207 | 0.74 | — | — | |
| SCHEMBL20515219 | 0.74 | — | — | |
| SCHEMBL217699 | 0.74 | — | — | |
| SCHEMBL3273348 | 0.73 | CA1 (0.35) | CA12CA1CA2CA9 | |
| Phosphine SCHEMBL22634022 | 0.73 | CA1 (0.35) | CA12CA1CA2CA9 | |
| SCHEMBL10775019 | 0.73 | CA1 (0.41) | CA12CA1CA2CA9 | |
| SCHEMBL9725970 | 0.73 | CA1 (0.41) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005117869-A1 | COMBINATIONS COMPRISING (S)-AMLODIPINE AND A CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITOR, AND METHODS FOR REDUCING HYPERTENSION | SEPRACOR INC. (US) | 2005-12-15 | — | — | WO | disclosed |