Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | TSHR | P16473 | 2/20 | 0.83 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271511 | 0.98 | CYP3A4 (0.79) | CYP3A4TSHRHPGDSMN1; SMN2LPAR3 | |
| SCHEMBL6272152 | 0.95 | CYP3A4 (0.83) | CYP3A4TSHRHPGDSMN1; SMN2LPAR3 | |
| SCHEMBL6271797 | 0.95 | CYP3A4 (0.75) | CYP3A4TSHRHPGDSMN1; SMN2LPAR3 | |
| SCHEMBL7596085 | 0.94 | CYP3A4 (0.73) | CYP3A4TSHRHPGDSMN1; SMN2LPAR3 | |
| SCHEMBL6266753 | 0.93 | CYP3A4 (0.72) | CYP3A4TSHRHPGDSMN1; SMN2LPAR3 | |
| SCHEMBL6269581 | 0.93 | CYP3A4 (0.72) | CYP3A4TSHRHPGDSMN1; SMN2LPAR3 | |
| SCHEMBL28375823 | 0.93 | CYP3A4 (0.94) | CYP3A4TSHRHPGDSMN1; SMN2LPAR3 | |
| SCHEMBL5427069 | 0.92 | CYP3A4 (0.84) | CYP3A4TSHRHPGDSMN1; SMN2LPAR3 | |
| SCHEMBL1295611 | 0.91 | CYP3A4 (0.74) | CYP3A4TSHRHPGDSMN1; SMN2LPAR3 | |
| SCHEMBL18444274 | 0.91 | CYP3A4 (0.69) | CYP3A4TSHRHPGDSMN1; SMN2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157055-B1 | THERMOSETTING POLY URETHANE/UREA-FORMING COMPOSITIONS | CROMPTON CORP (US) | 2005-12-14 | — | — | EP | disclosed |
| US-6369156-B1 | CURABLE MIXTURE; AROMATIC POLYAMINE CONTAINING THIOETHER GROUP, PHOSPHATE ESTER, AND ALDEHYDE OR ALDEHYDE-FORMING COMPOUND; DISCOLORATION INHIBITION | VANTICO INC. | 2002-04-09 | — | — | US | disclosed |
| EP-1157055-A1 | THERMOSETTING POLY URETHANE/UREA-FORMING COMPOSITIONS | Vantico AG (CH) | 2001-11-28 | — | — | EP | disclosed |
| EP-1097952-A1 | Polurethane/Polyurea-forming compositions | Vantico AG (CH) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000035983-A1 | THERMOSETTING POLY URETHANE/UREA-FORMING COMPOSITIONS | VANTICO AG (CH) | 2000-06-22 | — | — | WO | disclosed |