Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 8/20 | 0.53 |
| ▸ | FYN | P06241 | 11/20 | 0.51 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627396 | 1.00 | PIK3CA (0.53) | PIK3CAFYNHASPIN | |
| SCHEMBL627329 | 0.89 | PIK3CA (0.49) | PIK3CAFYNHASPIN | |
| SCHEMBL627327 | 0.89 | PIK3CA (0.49) | PIK3CAFYNHASPIN | |
| SCHEMBL626891 | 0.89 | PIK3CA (0.49) | PIK3CAFYNHASPIN | |
| SCHEMBL626893 | 0.89 | PIK3CA (0.49) | PIK3CAFYNHASPIN | |
| SCHEMBL627441 | 0.89 | FYN (0.63) | PIK3CAFYNHASPIN | |
| SCHEMBL627439 | 0.89 | FYN (0.63) | PIK3CAFYNHASPIN | |
| SCHEMBL624427 | 0.88 | PIK3CA (0.50) | PIK3CAFYNHASPIN | |
| SCHEMBL625300 | 0.86 | PIK3CA (0.51) | PIK3CAFYNHASPIN | |
| SCHEMBL625635 | 0.85 | PIK3CA (0.51) | PIK3CAFYNHASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |