Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.33 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3286185 | 0.89 | MAPT (0.50) | MAPTMAPK1GPR35ALDH1A1MEN1 | |
| SCHEMBL3283730 | 0.89 | MAPT (0.65) | MAPTMAPK1GPR35ALDH1A1MEN1 | |
| SCHEMBL3279594 | 0.85 | MAPT (0.67) | MAPTMAPK1GPR35ALDH1A1MEN1 | |
| SCHEMBL5702828 | 0.78 | MAPT (0.39) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3278014 | 0.76 | MAPK1 (0.37) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL10398537 | 0.73 | MAPK1 (0.35) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3283141 | 0.73 | MAPK1 (0.65) | MAPTMAPK1GPR35ALDH1A1MEN1 | |
| SCHEMBL3278985 | 0.73 | MAPT (0.65) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3279016 | 0.73 | MAPT (0.50) | MAPTMAPK1GPR35ALDH1A1KDM4E | |
| SCHEMBL3284952 | 0.73 | MAPT (0.50) | MAPTMAPK1GPR35ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606447-A1 | OXIDATION SYSTEM CONTAINING A MACROCYCLIC METAL COMPLEX, THE PRODUCTION THEREOF AND ITS USE | Lanxess B.V. (NL) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004083516-A1 | OXIDATION SYSTEM CONTAINING A MACROCYCLIC METAL COMPLEX, THE PRODUCTION THEREOF AND ITS USE | LANXESS B.V. (NL) | 2004-09-30 | — | — | WO | disclosed |