Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648427 | 0.85 | HDAC8 (0.45) | HDAC8CYP2A6 | |
| SCHEMBL6338912 | 0.79 | TSHR (0.38) | HDAC8CYP2A6 | |
| SCHEMBL1135060 | 0.75 | CHKA (0.41) | CYP2A6 | |
| SCHEMBL6267582 | 0.74 | HDAC8 (0.35) | HDAC8 | |
| SCHEMBL577736 | 0.74 | HDAC8 (0.67) | HDAC8CYP2A6 | |
| SCHEMBL30742715 | 0.71 | HDAC8 (0.33) | HDAC8CYP2A6 | |
| SCHEMBL5490090 | 0.70 | TSHR (0.35) | HDAC8 | |
| SCHEMBL7460666 | 0.69 | CHKA (0.35) | — | |
| Isonicotinonitrile SCHEMBL1135040 | 0.68 | TSHR (0.33) | HDAC8CYP2A6 | |
| SCHEMBL7460697 | 0.68 | CHKA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1046654-B1 | Olefin polymerization catalysts and olefin polymer production methods using said olefin polymerization catalysts | JSR CORP (JP) | 2005-06-29 | — | — | EP | claimed |
| US-6525150-B1 | Such as vanadium 2,2'-thiobis(6-t-butyl-4-methylphenyl) oxychloride complex, trimethylaluminum and N,N-dimethyl-anilinium tetrakis(pentafluorophenyl)borate; high degree of copolymerization | JSR CORPORATION (JP) | 2003-02-25 | — | — | US | claimed |
| EP-1046654-A1 | Olefin polymerization catalysts and olefin polymer production methods using said olefin polymerization catalysts | JSR Corporation (JP) | 2000-10-25 | — | — | EP | claimed |