Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.66 |
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | RECQL | P46063 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 7/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | DUSP22 | Q9NRW4 | 2/20 | 0.54 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908215 | 1.00 | MEN1 (0.66) | MEN1KMT2AMAPTRECQLKDM4E | |
| SCHEMBL3908212 | 1.00 | MEN1 (0.66) | MEN1KMT2AMAPTRECQLKDM4E | |
| SCHEMBL3892547 | 0.83 | MEN1 (0.71) | MEN1KMT2AMAPTRECQLKDM4E | |
| SCHEMBL3892542 | 0.83 | MEN1 (0.71) | MEN1KMT2AMAPTRECQLKDM4E | |
| SCHEMBL3895721 | 0.83 | CFTR (0.63) | MEN1KMT2AMAPTRECQLKDM4E | |
| SCHEMBL3895716 | 0.83 | CFTR (0.63) | MEN1KMT2AMAPTRECQLKDM4E | |
| SCHEMBL3890772 | 0.82 | KMT2A (0.64) | MEN1KMT2AMAPTRECQLKDM4E | |
| SCHEMBL3890778 | 0.82 | KMT2A (0.64) | MEN1KMT2AMAPTRECQLKDM4E | |
| SCHEMBL3897777 | 0.78 | MEN1 (0.65) | MEN1KMT2AMAPTRECQLKDM4E | |
| SCHEMBL3897872 | 0.78 | MAPT (0.65) | MEN1KMT2AMAPTRECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041951-A2 | RHODANINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | claimed |