Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627559 | 1.00 | MME (0.48) | MMETGFBR1PTGS1SLC7A11ACE | |
| SCHEMBL27820990 | 0.96 | MME (0.50) | MMETGFBR1PTGS1SLC7A11ACE | |
| SCHEMBL27820989 | 0.96 | MME (0.50) | MMETGFBR1PTGS1SLC7A11ACE | |
| SCHEMBL30011269 | 0.95 | ACE (0.51) | MMETGFBR1PTGS1SLC7A11ACE | |
| SCHEMBL30010203 | 0.95 | ACE (0.51) | MMETGFBR1PTGS1SLC7A11ACE | |
| SCHEMBL30011698 | 0.95 | ACE (0.51) | MMETGFBR1PTGS1SLC7A11ACE | |
| SCHEMBL29461530 | 0.95 | ACE (0.51) | MMETGFBR1PTGS1SLC7A11ACE | |
| Glycerin SCHEMBL28033837 | 0.94 | MME (0.43) | MMETGFBR1PTGS1SLC7A11ACE | |
| SCHEMBL30782821 | 0.89 | MME (0.45) | MMEPTGS1SLC7A11ACE | |
| SCHEMBL30288027 | 0.88 | ACE (0.51) | MMETGFBR1PTGS1SLC7A11ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979080-B9 | A METHOD OF MODULATING AN IMMUNE RESPONSE IN AN INFECTED MAMMAL BY TRANSMUCOSAL ADMINISTRATION OF MODULATING AGENT | UNIV JEFFERSON (US) | 2012-02-22 | — | — | EP | claimed |
| EP-0979080-B1 | A METHOD OF MODULATING AN IMMUNE RESPONSE IN AN INFECTED MAMMAL BY TRANSMUCOSAL ADMINISTRATION OF MODULATING AGENT | UNIV JEFFERSON (US) | 2011-07-13 | — | — | EP | claimed |
| EP-0431327-B1 | Synthetic vaccine for the specific induction of cytotoxic T-lymphocytes | HOECHST AG (DE) | 1996-04-24 | — | — | EP | claimed |
| EP-0431327-A1 | Synthetic vaccine for the specific induction of cytotoxic T-lymphocytes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-12 | — | — | EP | claimed |
| CN-108135999-A | For rabic human antibody and application thereof | 马萨诸塞大学 | 2018-06-08 | — | — | CN | disclosed |