SCHEMBL6276342

SCHEMBL6276342

O=C(NC(CO)(CO)CO)c1cc(C(=O)O)n(Cc2cc(-c3ccc(Cl)s3)on2)n1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.49
F2 P00734 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1456862 0.86 F10 (0.49) F10F2
SCHEMBL2781112 0.85 F10 (0.50) F10F2
SCHEMBL2780405 0.84 F10 (0.49) F10F2
SCHEMBL1455995 0.83 F10 (0.49) F10F2
SCHEMBL3839182 0.83 F10 (0.72) F10F2
SCHEMBL1456402 0.82 F10 (0.52) F10F2
SCHEMBL6279858 0.82 F10 (0.51) F10F2
SCHEMBL2780778 0.81 F10 (0.50) F10F2
SCHEMBL2782382 0.81 F10 (0.48) F10F2
SCHEMBL2781719 0.81 F10 (0.48) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1581523-A1 PYRAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS Aventis Pharma Deutschland GmbH (DE) 2005-10-05 EP claimed
WO-2004056815-A1 PYRAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-07-08 WO claimed