Dioxane

Dioxane

SCHEMBL627654

C1COCCO1.O=S(=O)=O

nearest known ligand 0.60

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Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.60
ALDH1A1 P00352 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
GAA P10253 1/20 0.32
CA12 O43570 1/20 0.30
CA7 P43166 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dioxane SCHEMBL27781593 1.00 TTR (0.60) TTRALDH1A1MEN1KMT2ATSHR
SCHEMBL27923295 0.82
Tetrahydrofuran SCHEMBL1373782 0.82
Dioxane SCHEMBL1109678 0.82 TTR (0.50) TTRALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL6898337 0.80
Dioxane SCHEMBL29287389 0.78
SCHEMBL11207601 0.78 TTR (1.00) TTRALDH1A1MEN1KMT2ATSHR
Dioxane SCHEMBL9836999 0.78
SCHEMBL6057268 0.78 TTR (1.00) TTRALDH1A1MEN1KMT2ATSHR
SCHEMBL3137753 0.78 TTR (1.00) TTRALDH1A1MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113563237-B 2-methoxyamino-4-substituted cyclohexane sulfonamide compound and preparation method and application thereof 沈阳农业大学 2023-07-04 CN claimed
CN-113402426-B N-substituted-3, 3-dimethyl-2-oxo-butanesulfonamide compound as well as preparation method and application thereof 沈阳农业大学 2023-05-26 CN claimed
US-20230151339-A1 ENGINEERED ARYL SULFATE-DEPENDENT ENZYMES GINKGO BIOWORKS, INC. 2023-05-18 US claimed
CN-114685398-B Cyclohexanothiadiazine compound and preparation method and application thereof 沈阳农业大学 2023-04-18 CN claimed
CN-114685398-A Cyclohexanothiadiazine compound and preparation method and application thereof 沈阳农业大学 2022-07-01 CN claimed
CN-113563238-A 2-phenoxyethylamino cyclohexane sulfonamide compound and preparation method and application thereof 沈阳农业大学 2021-10-29 CN claimed
CN-113563237-A 2-methoxy amino-4-substituted cyclohexyl sulfonamide compound and preparation method and application thereof 沈阳农业大学 2021-10-29 CN claimed
CN-113402426-A N-substituted-3, 3-dimethyl-2-oxobutanesulfonamide compound and preparation method and application thereof 沈阳农业大学 2021-09-17 CN claimed
CN-108440412-B 2-pyrazole amide cyclohexyl sulfonamide compound, preparation method and application thereof 沈阳农业大学 2021-04-13 CN claimed
CN-107417686-B Method for synthesizing avibactam sodium 北京化工大学 2020-04-28 CN claimed
US-5767235-A SULFATED TYOSINE NIPPON MINING COMPANY LIMITED (JP) 1998-06-16 US claimed
US-5686603-A DERIVED FROM CARBOHYDRATES, SUGARS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-11-11 US claimed
EP-0337738-B1 Process for producing a sulfonation product of conjugated diene, polymer of the sulfonation product and dispersion composition containing the sulfonation product and/or of the polymer JAPAN SYNTHETIC RUBBER CO LTD (JP) 1995-08-09 EP claimed
US-5095986-A Surfactant flooding TEXACO, INC. (US) 1992-03-17 US claimed
US-5095985-A Injection of a surfactant slug to improve oil recovery TEXACO INC. (US) 1992-03-17 US claimed
US-5094295-A Enhanced oil recovery using alkylated, sulfonated, oxidized lignin surfactants TEXACO INC. (US) 1992-03-10 US claimed
US-5081268-A Process for the preparation of oxetanes from 1,3-glycol monosulfates ARCO CHEMICAL TECHNOLOGY, INC. (US) 1992-01-14 US claimed
US-4739040-A Surfactants from lignin TEXACO INC. (US) 1988-04-19 US claimed
US-4480098-A Preparation of alkali metal thieno(furo)pyridines ELI LILLY AND COMPANY (US) 1984-10-30 US claimed
US-3985722-A Process for preparing N-higher aliphatic acyl derivatives of amino acids, peptides or proteins AJINOMOTO CO., INC. (JA) 1976-10-12 US claimed