Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.47 |
| ▸ | DNTT | P04053 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | GBA1 | P04062 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10875328 | 1.00 | POLA1 (0.47) | POLA1DNTTPOLBGAAGBA1 | |
| SCHEMBL2975191 | 0.93 | POLA1 (0.39) | POLA1DNTTPOLB | |
| SCHEMBL3007350 | 0.85 | POLA1 (0.31) | POLA1 | |
| SCHEMBL4146571 | 0.83 | POLA1 (0.41) | POLA1DNTTPOLBGAA | |
| SCHEMBL27578070 | 0.80 | POLA1 (0.38) | POLA1DNTTPOLBGAAGBA1 | |
| SCHEMBL28256306 | 0.79 | POLA1 (0.41) | POLA1DNTTPOLB | |
| SCHEMBL29192814 | 0.77 | POLA1 (0.39) | POLA1DNTTPOLB | |
| SCHEMBL29210938 | 0.77 | POLA1 (0.43) | POLA1DNTTPOLB | |
| SCHEMBL670329 | 0.76 | POLA1 (0.35) | POLA1GAA | |
| SCHEMBL11324268 | 0.76 | POLA1 (0.42) | POLA1DNTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005107788-A1 | INHIBITION OF ALLERGIC CONTACT DERMATITIS BY N-L-ALPHA-ASPARTYL-L-PHENYLALANINE 1-METHYL ESTER | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2005-11-17 | — | — | WO | disclosed |
| EP-0722463-B1 | METHODS AND COMPOSITION FOR THE MODULATION OF HOST IMMUNE RESPONSE TO ALLERGENS | ALLERGENE INC (US) | 2003-03-19 | — | — | EP | disclosed |
| US-5512283-A | VACCINATING WITH MONOCLONAL ANTIBODY | ALLERGENE, INC. (US) | 1996-04-30 | — | — | US | disclosed |