⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149393 | 0.81 | — | — | |
| Ammonia Solution, Strong SCHEMBL16760976 | 0.78 | — | — | |
| SCHEMBL9418943 | 0.78 | SLC1A1 (0.70) | — | |
| SCHEMBL21612697 | 0.74 | — | — | |
| Acetic Acid SCHEMBL8585948 | 0.73 | SLC1A1 (0.50) | — | |
| Acetic Acid SCHEMBL15055675 | 0.73 | SLC1A1 (0.50) | — | |
| Acetic Acid SCHEMBL15055605 | 0.73 | SLC1A1 (0.50) | — | |
| Acetic Acid SCHEMBL4056123 | 0.73 | SLC1A1 (0.50) | — | |
| SCHEMBL36647 | 0.71 | — | — | |
| SCHEMBL542313 | 0.71 | FOLH1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419442-B9 | 3D MATRICES OF HUMAN ELASTIN-LIKE POLYPEPTIDES AND METHODS OF PREPARATION THEREOF | UNIVERSITA' DEGLI STUDI DI TRIESTE (IT) | 2017-01-18 | — | — | EP | disclosed |
| EP-2419442-B1 | 3D MATRICES OF HUMAN ELASTIN-LIKE POLYPEPTIDES AND METHODS OF PREPARATION THEREOF | UNIV DEGLI STUDI TRIESTE (IT) | 2016-11-16 | — | — | EP | disclosed |
| EP-2419442-A1 | 3D MATRICES OF HUMAN ELASTIN-LIKE POLYPEPTIDES AND METHOD OF PREPARATION THEREOF | Universita' Degli Studi Di Trieste (IT) | 2012-02-22 | — | — | EP | disclosed |
| US-8017394-B2 | Propagating cartilage tissues from chrondrocytes resistant to immune mediated xenograft rejection | ISTO TECHNOLOGIES, INC. (US) | 2011-09-13 | — | — | US | disclosed |
| WO-2010119420-A1 | 3D MATRICES OF HUMAN ELASTIN-LIKE POLYPEPTIDES AND METHOD OF PREPARATION THEREOF | UNIVERSITA' DEGLI STUDI DI TRIESTE (IT) | 2010-10-21 | — | — | WO | disclosed |
| US-20080081369-A1 | Method for Chondrocyte Expansion with Phenotype Retention | ISTO TECHNOLOGIES, INC. (US) | 2008-04-03 | — | — | US | disclosed |